2014 consensus for the use of alcohol markers in hair for assessment of both abstinence and chronic excessive alcohol consumption.

نویسنده

  • Pascal Kintz
چکیده

1.1 The direct determination of ethanol itself in hair is not possible due to its volatility and its potential absorption from external sources. Instead, the minor ethanol metabolites ethyl glucuronide (EtG) and/or fatty acid ethyl esters (FAEEs) can be measured in hair as direct markers of alcohol consumption. 1.2 In this consensus FAEEs are defined as: ethyl myristate, ethyl palmitate, ethyl oleate and ethyl stearate. For interpretation, the sum of the concentrations of these four esters should be used. 1.3 It is not advisable to use the results of hair testing for alcohol markers in isolation; all relevant factors surrounding a case 2.6 Cosmetic treatments 2.6.1 The concentration of EtG and FAEEs in hair can be influenced by cosmetic treatments and thermal hair straightening tools. 2.6.2 The type of cosmetic hair treatment should be documented during sampling and considered during interpretation. 2.6.3 Bleaching, perming and dying of hair may lead to lower concentrations of EtG or false-negative results; and may also influence concentrations of FAEEs. 2.6.4 EtG appears not to be influenced by hairspray, gel, wax, oil, grease or ethanol-containing hair care products. 2.6.5 Use of ethanol-containing hair care products (e.g. hair

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Biochemical Markers of Acute and Chronic Ethanol Use: Forensic and Clinical Applications

Background: The analysis of ethanol in bio-samples is an important method for determination of acute alcohol use/abuse both in clinical and forensic toxicology. In forensic cases, it is known that micro-organisms involved in the postmortem putrefaction process can produce alcohol and when the body has been traumatized. In clinical setting, post-ingestion time has a critical role for determinati...

متن کامل

Combining serum carbohydrate-deficient transferrin and hair ethyl glucuronide to provide optimal information on alcohol use.

Weykamp et al. recently reported on their efforts toward the harmonization of carbohydrate-deficient transferrin (CDT) measurements in serum (1). Alcohol biomarkers play a key role in the identification of alcohol abuse, a chronic disorder with enormous health and legal implications. CDT is a widely used biomarker for the detection of excessive alcohol use that has a high diagnostic sensitivity...

متن کامل

Alcohol and Lactation

Background: Breastfeeding is the safest and best method for nurturing infant growth and health. While the harmful effects of alcohol during pregnancy are well-established, the consequences of alcohol intake during lactation have been far less examined. The effects of alcohol intake with large amounts noted on the infant include drowsiness, diaphoresis, deep sleep, weakness, decrease in linear g...

متن کامل

Complications of Alcohol Use in Pregnancy

Background: Alcohol is a potent teratogen and alcohol use in pregnancy and the periconception period can cause many complications in mother, fetus and neonate.  Discussion: Alcohol in the mother's blood passes through the placenta to the baby through the umbilical cord. Drinking alcohol during pregnancy can cause miscarriage, stillbirth, and a range of lifelong disorders. Alcohol-related birth ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Forensic science international

دوره 249  شماره 

صفحات  -

تاریخ انتشار 2015